Isotopically Labeled Compounds
Medchemexpress LLC (E)-2,3',4,5'-tetramethoxystilbene | 24144-92-1 | 99.4% | 300.35 | 1 ML
TMS ((E)-2,3′,4,5′-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC50 of 6 nM and a Ki value of 3 nM. It shows a lesser inhibitory effect on CYP1A1 (IC50=300 nM) and CYP1A2 (IC50=3.1 μM). This methylated derivative of resveratrol possesses anti-cancer activity.
- Selective and competitive CYP1B1 inhibitor
- Possesses anti-cancer activity
- IC50 for CYP1B1 is 6 nM
- IC50 for CYP1A1 is 300 nM
- IC50 for CYP1A2 is 3.1 μM
Cambridge Isotope Laboratories BROMOBENZENE (D5, 99.5%), 5 G, 4165-57-5
BROMOBENZENE (D5, 99.5%), 5 G, 4165-57-5
Sigma Aldrich Fine Chemicals Biosciences Dichloromethane-d2|1665-00-5 | MFCD00000882 | 10X0.6ml
Dichloromethane-d2 | Purity: 99.9 atom % D | MW: 86.94 | 1665-00-5 | MFCD00000882 | 10X0.6ml
Cambridge Isotope Laboratories Acetonitrile-D3 100% | 2206-26-0 | MFCD00001881 | 10 x 0.75 mL
Acetonitrile-D3 100% | Purity: 99.5% | Mol Wt: 44.07 | 2206-26-0 | MFCD00001881 | 10 x 0.75 mL
Sigma Aldrich Fine Chemicals Biosciences Methanol d4 99.8 atom D c50G
Methanol-d4 is a deuterated NMR solvent containing 0.03 % (v/v) TMS (trimethylsilane). It is useful in NMR-based research and analyses.
Cambridge Isotope Laboratories N,n-dimethylformamide-d7 (d, 99.5%), 4472-41-7, MFCD00003286, 10 g
Chemical Formula: (CD3)2NCDO, MW: 80.14, 99.5%, Synonyms: DMF-d7, Heptadeutero-N,N-dimethylformamide, Dimethyl formamide, N-Formyldimethylamine.
Cambridge Isotope Laboratories Sodium D-3-hydroxybutyrate | 13613-65-5 | MFCD00077788 | 0.5g
Sodium D-3-hydroxybutyrate | Putity: 97% | MW: 130.06 | 13613-65-5 | MFCD00077788 | 0.5g
Cayman Chemical Sphingosine d18 1
Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine inhibits PKC and phosphatidic acid phosphohydrolase, whereas it activates PLD and DAG kinase. Phosphorylation of sphingosine by SPHK 1 and SPHK 2 produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.
Medchemexpress LLC Pencycuron-d5 | 83286-58-2 | 99.90% | 1 MG
Pencycuron-d5 is a deuterium-labeled version of Pencycuron, identified as a benzoylurea fungicide. Its fungicidal action involves inhibiting the synthesis of fungal cell walls. This compound can be utilized in research focused on controlling fungal diseases in crops, including conditions such as sheath blight, powdery mildew, and late blight.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Methyl nicotinate-d4 | 345909-99-1 | 99.5% | 50 MG
Methyl nicotinate-d4 is the deuterium labeled Methyl nicotinate, used as an active ingredient in over-the-counter topical preparations for muscle and joint pain. It is also suitable for use as a tracer or an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotope of hydrogen
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Cayman Chemical ResolvIn D3 methyl ester 100UG
A methyl ester form of resolvin D3; may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties
Medchemexpress LLC Octanal-d16 | 1219794-66-7 | 10 MG
Octanal-d16 is the deuterium labeled Octanal, a fragrant aldehyde with antioxidant and antibacterial activity. It exhibits cytotoxicity towards HeLa cells with an IC50 value of 3.5 μg/mL. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cambridge Isotope Laboratories ACETONITRILE (15N, 98%+), 0.5 G, 14149-39-4
ACETONITRILE (15N, 98%+), 0.5 G, 14149-39-4
Cayman Chemical Prostaglandin D2 methyl ester
PGD2 methyl ester is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}